Cytomegalovirus Glycoprotein B Groups Associated with Retinitis in AIDS

Cytomegalovirus glycoprotein B genotyping in ocular fluids and blood of AIDS patients with cytomegalovirus retinitis.

PURPOSE To determine the frequency of cytomegalovirus glycoprotein B (gB) genotypes in clinical samples of ocular fluids of patients with acquired immune deficiency syndrome (AIDS) who have cytomegalovirus retinitis and to compare these with the cytomegalovirus gB genotype in paired peripheral blood leukocytes. METHODS Glycoprotein B genotypes of cytomegalovirus genomic DNA were determined in...

Cytomegalovirus retinitis in AIDS.

Cytomegalovirus retinitis is common in adults with AIDS but has been reported infrequently in children with perinatally acquired HIV infection. The cases are presented of two infants with vertically acquired HIV infection who developed disseminated cytomegalovirus infection and retinitis, and who posed difficult management issues.

'Creeping' cytomegalovirus retinitis in AIDS.

The management of cytomegalovirus retinitis in AIDS.

Cytomegalovirus (CMV) shares many properties with other members of the herpesvirus family it exhibits latency, reactivates under suitable conditions to cause human disease, and it is incurable. CMV is the primary opportunistic viral infection in the immunosuppressed person and gives rise to a wide spectrum of disease. CMV is a major cause ofmorbidity and mortality among patients with AIDS, and ...

Cytomegalovirus retinitis in HIV/AIDS patients

UNLABELLED Human immunodeficiency virus (HIV) has the ability to affect any organ in the body. In 70% of HIV-infected patients ocular manifestations were observed, which in the vast majority reflect the systemic disease and may be the first sign of a disseminated infection. AIM The purpose of this paper is to determine the prevalence and the clinical aspects of cytomegalovirus retinitis in HI...